In vitro antifungal activity of terpinen-4-ol, eugenol, carvone, 1,8-cineole (eucalyptol) and thymol against mycotoxigenic plant pathogens

Food Addit Contam Part A Chem Anal Control Expo Risk Assess. 2012;29(3):415-22. doi: 10.1080/19440049.2011.643458. Epub 2012 Jan 19.

Abstract

The aim of this study was to examine the effect of five naturally occurring compounds from essential oils on 10 different species of mycotoxigenic fungi involved in several plant diseases. The antifungal activities of terpinen-4-ol, eugenol, carvone, 1,8-cineole (eucalyptol) and thymol were observed in vitro on Fusarium subglutinans, Fusarium cerealis, Fusarium verticillioides, Fusarium proliferatum, Fusarium oxysporum, Fusarium sporotrichioides, Aspergillus tubingensis, Aspergillus carbonarius, Alternaria alternata and Penicillium sp. The naturally occurring compounds tested showed toxic effects on in vitro mycelium growth of all fungal species but with different level of potency. The results are encouraging for further investigations of in planta antifungal activities of these essential oils components.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Alternaria / drug effects
  • Alternaria / metabolism
  • Aspergillus / drug effects
  • Aspergillus / metabolism
  • Cyclohexane Monoterpenes
  • Cyclohexanols / adverse effects
  • Cyclohexanols / pharmacology
  • Eucalyptol
  • Eugenol / adverse effects
  • Eugenol / pharmacology*
  • Fungicides, Industrial / adverse effects
  • Fungicides, Industrial / pharmacology*
  • Fusarium / drug effects
  • Fusarium / growth & development
  • Fusarium / metabolism
  • Germination / drug effects
  • Hordeum / drug effects
  • Hordeum / growth & development
  • Hyphae / drug effects
  • Hyphae / metabolism
  • Inhibitory Concentration 50
  • Mitosporic Fungi / drug effects*
  • Mitosporic Fungi / growth & development
  • Mitosporic Fungi / metabolism
  • Monoterpenes / adverse effects
  • Monoterpenes / pharmacology*
  • Mycotoxins / metabolism
  • Oils, Volatile / chemistry
  • Penicillium / drug effects
  • Penicillium / metabolism
  • Plant Diseases / microbiology
  • Plant Diseases / prevention & control
  • Seeds / drug effects
  • Seeds / growth & development
  • Terpenes / adverse effects
  • Terpenes / pharmacology
  • Thymol / adverse effects
  • Thymol / pharmacology*
  • Trichothecenes / metabolism

Substances

  • Cyclohexane Monoterpenes
  • Cyclohexanols
  • Fungicides, Industrial
  • Monoterpenes
  • Mycotoxins
  • Oils, Volatile
  • Terpenes
  • Trichothecenes
  • Thymol
  • Eugenol
  • terpinenol-4
  • carvone
  • deoxynivalenol
  • Eucalyptol