Drug-polyester conjugated nanoparticles for cancer drug delivery

Annu Int Conf IEEE Eng Med Biol Soc. 2011:2011:8337-9. doi: 10.1109/IEMBS.2011.6092056.

Abstract

We report here the synthesis of camptothecin-polylactide conjugate via camptothecin-initiated lactide polymerization and the formation of nanoconjugates for drug delivery applications.

Publication types

  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Antineoplastic Agents / pharmacology*
  • Camptothecin / chemistry
  • Camptothecin / pharmacology
  • Catalysis / drug effects
  • Chromatography, High Pressure Liquid
  • Drug Delivery Systems / methods*
  • Nanoparticles / chemistry*
  • Neoplasms / drug therapy*
  • Pharmaceutical Preparations / chemistry*
  • Polyesters / chemistry*
  • Succinic Anhydrides / chemistry

Substances

  • Antineoplastic Agents
  • Pharmaceutical Preparations
  • Polyesters
  • Succinic Anhydrides
  • poly(lactide)
  • succinic anhydride
  • Camptothecin