A bio-impedance probe to assess liver steatosis during transplant surgery

Annu Int Conf IEEE Eng Med Biol Soc. 2011:2011:4792-5. doi: 10.1109/IEMBS.2011.6091187.

Abstract

This work addresses the design of a bioimpedance probe to assess steatosis on the exposed liver in the donor during liver transplant surgery. Whereas typically bioimpedance uses needle probes to avoid surface effects, for clinical reasons a non-penetrative probe is required. In addition the need to ensure that the measurement is representative of the bulk tissue suggests a larger probe than is normally used to ensure a sufficiently large measurement volume. Using a simple model, simulations and tests on bovine liver, this paper investigates the relationship between probe dimensions and depth of measurement penetration and investigates the accuracy which might be expected in a configuration suitable for use in the operating theatre on intact but exposed livers. A probe using ECG electrodes is proposed and investigated.

MeSH terms

  • Animals
  • Cattle
  • Electric Impedance
  • Fatty Liver / pathology*
  • Finite Element Analysis
  • Humans
  • Models, Theoretical
  • Transplantation*