Using microelectrode models for real time cell-culture monitoring

Alberto Yúfera; Paula Daza; Daniel Cañete

doi:10.1109/IEMBS.2011.6090989

Using microelectrode models for real time cell-culture monitoring

Annu Int Conf IEEE Eng Med Biol Soc. 2011:2011:3983-6. doi: 10.1109/IEMBS.2011.6090989.

Authors

Alberto Yúfera¹, Paula Daza, Daniel Cañete

Affiliation

¹ Seville Microelectronics Institute, IMSE-CNM,Seville Uni. Av Americo Vespucio, 41092 Seville, Spain. yufera@imse-cnm.csic.es

PMID: 22255212
DOI: 10.1109/IEMBS.2011.6090989

Abstract

This paper proposes a cell-microelectrode model for cell biometry applications, based on the area overlap as main parameter. The model can be applied to cell size identification, cell count, and their extension to cell growth and dosimetry protocols. Experiments performed with comercial electrodes are presented, illustrating a procedure to obtain cell number in both growth and dosimetry processes. Results obtained for the AA8 cell line are promising.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Animals
Cells, Cultured
Cricetinae
Microelectrodes*
Models, Theoretical*