A novel pulse morphology-based approach for estimation of blood pressure from non-invasive oscillometric blood pressure measurement is presented. Quantitative measures that describe the pulse morphology are utilized to obtain the estimates of mean arterial, systolic, and diastolic pressures. Preliminary results obtained from a small set of measurements are used to demonstrate the feasibility of the proposed approach. The estimates obtained through pulse morphology-based approach is compared with those obtained from a commercial blood pressure device.