Postprandial energy metabolism in the regulation of body weight: is there a mechanistic role for dietary calcium?

Nutrients. 2010 Jun;2(6):586-98. doi: 10.3390/nu2060586. Epub 2010 May 28.

Abstract

There has been much interest in the mechanisms by which calcium may attenuate weight gain or accelerate body fat loss. This review focuses on postprandial energy metabolism and indicates that dietary calcium increases whole body fat oxidation after single and multiple meals. There is, as yet, no conclusive evidence for a greater diet induced thermogenesis, an increased lipolysis or suppression of key lipogenic enzyme systems. There is however convincing evidence that higher calcium intakes promote a modest energy loss through increased fecal fat excretion. Overall, there is a role for dietary calcium in human energy metabolism. Future studies need to define threshold intakes for metabolic and gastrointestinal outcomes.

Keywords: calcium; fat oxidation; fecal fat; lipolysis; obesity; postprandial; thermogenesis.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Adipose Tissue / metabolism
  • Calcium, Dietary / pharmacology*
  • Energy Metabolism / physiology*
  • Feces / chemistry
  • Female
  • Humans
  • Lipogenesis / drug effects
  • Lipolysis / drug effects
  • Male
  • Postprandial Period / drug effects*
  • Thermogenesis / drug effects

Substances

  • Calcium, Dietary