DNA microarrays on silicon surfaces through thiol-ene chemistry

Chem Commun (Camb). 2012 Feb 18;48(15):2116-8. doi: 10.1039/c2cc17321b. Epub 2012 Jan 16.

Abstract

The potential of thiol-ene chemistry as a selective strategy to functionalize silicon materials for DNA microarraying is demonstrated and applied to discriminate genetic variations.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Base Sequence
  • Biotin / chemistry
  • DNA Probes / chemistry
  • Oligonucleotide Array Sequence Analysis*
  • Silicon / chemistry*
  • Sulfhydryl Compounds / chemistry*
  • Surface Properties

Substances

  • DNA Probes
  • Sulfhydryl Compounds
  • Biotin
  • Silicon