Can we prevent food allergy by manipulating the timing of food exposure?

Immunol Allergy Clin North Am. 2012 Feb;32(1):51-65. doi: 10.1016/j.iac.2011.11.007. Epub 2011 Dec 16.

Abstract

Prevention of food allergies by maternal and infant feeding practices serves as a simple, inexpensive approach to address the growing number of subjects with food allergies in comparison with any emerging interventional therapies for existing food allergies, such as oral immunotherapy. This article provides a careful evaluation of the rationale and existing data on the effect of timing of the introduction of food allergens (during pregnancy, lactation, and early childhood) on the development of specific food allergies.

Publication types

  • Review

MeSH terms

  • Adolescent
  • Animals
  • Breast Feeding
  • Child
  • Child, Preschool
  • Disease Models, Animal
  • Egg Hypersensitivity / epidemiology
  • Egg Hypersensitivity / prevention & control
  • Feeding Behavior*
  • Female
  • Food / adverse effects
  • Food Hypersensitivity / diagnosis
  • Food Hypersensitivity / epidemiology*
  • Food Hypersensitivity / prevention & control*
  • Humans
  • Immune Tolerance
  • Immunoglobulin E / immunology
  • Mice
  • Milk Hypersensitivity / epidemiology
  • Milk Hypersensitivity / prevention & control
  • Peanut Hypersensitivity / epidemiology
  • Peanut Hypersensitivity / prevention & control
  • Pregnancy
  • Skin Tests

Substances

  • Immunoglobulin E