Time to reflect on surgery and neuro-intervention for intracranial atherosclerotic diseases

George Kwok Chu Wong; Wai Sang Poon

doi:10.1016/j.jocn.2011.07.019

Time to reflect on surgery and neuro-intervention for intracranial atherosclerotic diseases

J Clin Neurosci. 2012 Feb;19(2):222-3. doi: 10.1016/j.jocn.2011.07.019. Epub 2012 Jan 12.

Authors

George Kwok Chu Wong¹, Wai Sang Poon

Affiliation

¹ Division of Neurosurgery, Department of Surgery, Prince of Wales Hospital, 4/F, Clinical Science Building, The Chinese University of Hong Kong, 1 Ngan Shing Street, Shatin, New Territories, Hong Kong, China. georgewong@surgery.cuhk.edu.hk

PMID: 22244016
DOI: 10.1016/j.jocn.2011.07.019

Abstract

In view of the early results and halt of recruitment from both the Carotid Occlusion Surgery Study (COSS) and Stenting and the Aggressive Medical Therapy for Preventing Recurrent Stroke in Intracranial Stenosis (SAMMPRIS) study we should seize this opportunity to reflect on future directions, rather than abandoning these procedures, during this period of disillusionment. We here suggest the reasons for the failure of these two clinical trials and review future directions for researche in cerebral revascularization.

Publication types

Review

MeSH terms

Carotid Artery Diseases / diagnosis
Carotid Artery Diseases / surgery
Carotid Stenosis / diagnosis
Carotid Stenosis / surgery
Clinical Trials as Topic / methods
Clinical Trials as Topic / trends
Humans
Intracranial Arteriosclerosis / diagnosis*
Intracranial Arteriosclerosis / surgery*
Neurosurgical Procedures / instrumentation
Neurosurgical Procedures / methods*
Neurosurgical Procedures / trends
Stents
Stroke / diagnosis
Stroke / surgery