In this work we demonstrate chiral recognition of (+)- and (-)-ephedrine using a cyclodextrin-containing polymer. The supramolecular structures obtained by complexation of ephedrine and cyclodextrin were verified by 2-D ROESY NMR measurements. Dynamic light scattering showed clear differences in the mean coil size.
Keywords: chiral recognition; cyclodextrins; ephedrine; host–guest interaction; stimuli-responsive polymer.