[Ketamine-induced vesicopathy]

Psychiatr Prax. 2012 Jan;39(1):43-5. doi: 10.1055/s-0031-1292789. Epub 2012 Jan 10.
[Article in German]

Abstract

We report about a 25-year-old patient with transnasal ketamine abuse over years presenting with severe irritative urinary dysfunction (imperative urinary urgency, pollakisuria, dysuria) and severe alguria. Cystoscopia showed ketamine-induced vesicopathy with errosive cystitis; other etiologies could be excluded. Despite serious effort the patient was not motivated for abstinence from ketamine. After two ineffecient therapies with botulinum toxin A (200 and 400 I. E.) injected into the bladder, a prostate preserving cystectomia and ileum neobladder were mandatory.

Publication types

  • Case Reports

MeSH terms

  • Administration, Intranasal
  • Administration, Intravesical
  • Adult
  • Analgesics / administration & dosage
  • Analgesics / adverse effects*
  • Botulinum Toxins, Type A / administration & dosage
  • Cystectomy
  • Cystitis / chemically induced
  • Cystitis / diagnosis
  • Cystitis / rehabilitation
  • HIV Seropositivity / physiopathology
  • HIV Seropositivity / psychology
  • Humans
  • Ketamine / administration & dosage
  • Ketamine / adverse effects*
  • Male
  • Patient Compliance / psychology
  • Substance-Related Disorders / complications*
  • Substance-Related Disorders / diagnosis*
  • Substance-Related Disorders / rehabilitation
  • Urinary Diversion
  • Urination Disorders / chemically induced*
  • Urination Disorders / diagnosis
  • Urination Disorders / rehabilitation

Substances

  • Analgesics
  • Ketamine
  • Botulinum Toxins, Type A