Clarithromycin potentiates tyrosine kinase inhibitor treatment in patients with resistant chronic myeloid leukemia

MeSH terms

• Adult
• Aged
• Antineoplastic Combined Chemotherapy Protocols / therapeutic use*
• Clarithromycin / administration & dosage
• Dasatinib
• Drug Resistance, Neoplasm / drug effects*
• Drug Synergism
• Female
• Fusion Proteins, bcr-abl / genetics
• Humans
• In Situ Hybridization, Fluorescence
• Leukemia, Myelogenous, Chronic, BCR-ABL Positive / drug therapy*
• Leukemia, Myelogenous, Chronic, BCR-ABL Positive / genetics
• Leukemia, Myelogenous, Chronic, BCR-ABL Positive / pathology
• Male
• Middle Aged
• Protein Kinase Inhibitors / administration & dosage
• Pyrimidines / administration & dosage
• Thiazoles / administration & dosage
• Transcription, Genetic / drug effects
• Treatment Outcome