Compartmentation of GABA metabolism raises intriguing questions

Barry J Shelp; Robert T Mullen; Jeffrey C Waller

doi:10.1016/j.tplants.2011.12.006

Compartmentation of GABA metabolism raises intriguing questions

Trends Plant Sci. 2012 Feb;17(2):57-9. doi: 10.1016/j.tplants.2011.12.006. Epub 2012 Jan 7.

Authors

Barry J Shelp¹, Robert T Mullen, Jeffrey C Waller

Affiliation

¹ Department of Plant Agriculture, University of Guelph, Guelph, ON, Canada N1G 2W1. bshelp@uoguelph.ca

PMID: 22226724
DOI: 10.1016/j.tplants.2011.12.006

Abstract

This synopsis covers the compartmentation of γ-aminobutyrate (GABA) metabolism, highlighting recent progress with Arabidopsis (Arabidopsis thaliana) and raising questions about mitochondrial GABA and succinic semialdehyde (SSA) transport, the fate of succinic semialdehyde once it exits mitochondria, and biochemical interactions between GABA metabolism and related processes such as photorespiration.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Arabidopsis / metabolism*
Biological Transport
Mitochondria / metabolism
Oxidation-Reduction
Substrate Specificity
gamma-Aminobutyric Acid / metabolism*

Substances

gamma-Aminobutyric Acid