Improved lycopene production by Blakeslea trispora with isopentenyl compounds and metabolic precursors

Biotechnol Lett. 2012 May;34(5):849-52. doi: 10.1007/s10529-011-0839-6. Epub 2011 Dec 30.

Abstract

The highest lycopene production in mated cultures of Blakeslea trispora was 578 mg/l by adding 42 mg geraniol/l to the medium after 48 h of growth. The control gave 317 mg/l. Adding isopentenyl alcohol at 40 mg/l, mevalonic acid at 17.5 mg/l or dimethyl allyl alcohol at 150 mg, each after 36 h growth, gave lycopene yields 62, 45 and 47%, respectively, higher than the control.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Carotenoids / biosynthesis*
  • Culture Media / chemistry
  • Lycopene
  • Mucorales / metabolism*
  • Pentanols / metabolism*

Substances

  • Culture Media
  • Pentanols
  • Carotenoids
  • Lycopene