Genetic diversity and drug susceptibility of Mycobacterium tuberculosis isolates from Zunyi, one of the highest-incidence-rate areas in China

J Clin Microbiol. 2012 Mar;50(3):1043-7. doi: 10.1128/JCM.06095-11. Epub 2012 Jan 11.

Abstract

Mycobacterium tuberculosis isolates from Zunyi were found more diversified but clustered less frequently to the Beijing family compared to isolates from other areas of China. These observations, on top of the fact that the Zunyi area has a high prevalence of multidrug-resistant tuberculosis (MDR-TB), support the notion that Beijing family isolates may not be linked to MDR-TB.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Antitubercular Agents / pharmacology*
  • China / epidemiology
  • Cluster Analysis
  • Drug Resistance, Multiple, Bacterial*
  • Genetic Variation*
  • Humans
  • Incidence
  • Microbial Sensitivity Tests
  • Molecular Typing
  • Mycobacterium tuberculosis / classification*
  • Mycobacterium tuberculosis / drug effects*
  • Mycobacterium tuberculosis / genetics
  • Mycobacterium tuberculosis / isolation & purification
  • Tuberculosis / epidemiology*
  • Tuberculosis / microbiology*

Substances

  • Antitubercular Agents