The conformation of the title mol-ecule, C(25)H(23)FN(4)O, is mainly determined by an intra-molecular N-H⋯N hydrogen bond closing a six-membered ring and the dihedral angles between the pyrimidine ring and the three benzene rings which are 12.8 (2), 12.0 (2) and 86.1 (2)°. An intra-molecular N-H⋯F inter-action also occurs. The crystal stucture is stabilized by weak C-H⋯O and C-H⋯π inter-actions. An inter-molecular N-H⋯N inter-action is also observed.