Myc target miRs and liver cancer: small molecules to get Myc sick

Gastroenterology. 2012 Feb;142(2):214-8. doi: 10.1053/j.gastro.2011.12.023. Epub 2011 Dec 16.

Authors

Marie-Annick Buendia¹, Ludovic Bourre, Stefano Cairo

Affiliation

¹ INSERM Unit U785 Pathogenesis and Treatment of Fulminant Hepatitis and Primary Liver Cancer, Hepato-Biliary Center, Paul Brousse Hospital, Villejuif, France.

PMID: 22178210
DOI: 10.1053/j.gastro.2011.12.023

No abstract available

Publication types

Review

MeSH terms

Biomarkers, Tumor / genetics
Biomarkers, Tumor / metabolism*
Carcinoma, Hepatocellular / genetics*
Carcinoma, Hepatocellular / metabolism
Carcinoma, Hepatocellular / therapy
Gene Expression Regulation, Neoplastic
Genes, myc / physiology*
Genetic Therapy
Hepatoblastoma / genetics*
Hepatoblastoma / metabolism
Hepatoblastoma / therapy
Humans
Liver Neoplasms / genetics*
Liver Neoplasms / metabolism
Liver Neoplasms / therapy
MicroRNAs / metabolism*
MicroRNAs / therapeutic use
Proto-Oncogene Proteins c-myc / genetics
Proto-Oncogene Proteins c-myc / metabolism*

Substances

Biomarkers, Tumor
MYC protein, human
MicroRNAs
Proto-Oncogene Proteins c-myc