Abstract
Three new rhodamine-based probes Y1-Y3 were synthesized as "off-on" chemosensors for Fe(3+) imaging in living cells. The recognizing behaviors were investigated both experimentally and computationally. The crystal structure of the complex Y3-Fe(3+) revealed that Fe(3+) preferred to coordinate with the N atom of benzothiazole moiety rather than the O atom of carboxyl group.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Benzothiazoles / chemistry
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Chemistry Techniques, Analytical / methods
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Ferric Compounds / chemistry*
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Fluorescent Dyes / chemistry*
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HeLa Cells / metabolism
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Humans
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Iron / analysis*
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Microscopy, Electron, Scanning / methods
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Molecular Imaging / methods
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Nitrogen / chemistry
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Oxygen / chemistry
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Rhodamines / chemistry*
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Sensitivity and Specificity
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Spectrophotometry, Infrared
Substances
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Benzothiazoles
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Ferric Compounds
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Fluorescent Dyes
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Rhodamines
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Iron
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benzothiazole
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Nitrogen
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Oxygen