Chitosan fibers modified with HAp/β-TCP nanoparticles

Int J Mol Sci. 2011;12(11):7286-300. doi: 10.3390/ijms12117286. Epub 2011 Oct 25.

Abstract

This paper describes a method for preparing chitosan fibers modified with hydroxyapatite (HAp), tricalcium phosphate (β-TCP), and HAp/β-TCP nanoparticles. Fiber-grade chitosan derived from the northern shrimp (Pandalus borealis) and nanoparticles of tricalcium phosphate (β-TCP) and hydroxyapatite (HAp) suspended in a diluted chitosan solution were used in the investigation. Diluted chitosan solution containing nanoparticles of Hap/β-TCP was introduced to a 5.16 wt% solution of chitosan in 3.0 wt% acetic acid. The properties of the spinning solutions were examined. Chitosan fibers modified with nanoparticles of HAp/β-TCP were characterized by a level of tenacity and calcium content one hundred times higher than that of regular chitosan fibers.

Keywords: calcium phosphate; chitosan fibers; mechanical properties; nanoparticles.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Calcium Phosphates / chemistry*
  • Chitosan / chemistry*
  • Durapatite / chemistry*
  • Nanoparticles / chemistry*
  • Pandalidae
  • Solutions / chemistry

Substances

  • Calcium Phosphates
  • Solutions
  • beta-tricalcium phosphate
  • Chitosan
  • Durapatite