Supramolecular electrostatic nanoassemblies for bacterial forensics

Chemistry. 2012 Jan 16;18(3):756-9. doi: 10.1002/chem.201103237. Epub 2011 Dec 9.

Abstract

Electrostatic nanoassemblies were employed to identify bacterial growth conditions. They comprise a cationic conjugated oligoelectrolyte and fluorescein-tagged ssDNA and were optimized with a hybrid, computational neural network model. The photoluminescence spectra contained the oligomer and sensitized fluorescein emission. The spectra changed depending on the growth history of the bacteria introduced (see figure).

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Biosensing Techniques
  • DNA, Single-Stranded / chemistry
  • Escherichia coli / chemistry*
  • Fluorescence Resonance Energy Transfer
  • Fluorescent Dyes* / chemistry
  • Molecular Structure
  • Nanotechnology*

Substances

  • DNA, Single-Stranded
  • Fluorescent Dyes