The effects of vestibular stimulation rate and magnitude of acceleration on central pattern generation for chest wall kinematics in preterm infants

J Perinatol. 2012 Aug;32(8):614-20. doi: 10.1038/jp.2011.177. Epub 2011 Dec 8.

Abstract

Objective: To examine the role of vestibular inputs on respiratory and oromotor systems in healthy preterm infants.

Study design: A total of 27 preterm infants were quasi-randomly assigned to either the VestibuGlide treatment or control groups. VestibuGlide infants were held in a developmentally supportive position, given a pacifier and received a series of vestibular stimuli, counterbalanced across rate and acceleration conditions, 15 min 3 times per day for 10 days. The control infants were also held in a developmentally supportive position, given a pacifier for 15 min 3 times per day for 10 days but did not receive the VestibuGlide stimulation.

Result: A multi-level regression model revealed that treatment infants increased their respiratory rate in response to vestibular stimulus, and that the highest level of vestibular acceleration delivered to the infants (0.51 ms(-2)) resulted in a significant increase in breaths per minute.

Conclusion: Vestibular stimulation delivered to preterm infants before scheduled feeds effectively modulates respiratory rate and resets the respiratory central pattern generator.

Publication types

  • Research Support, N.I.H., Extramural

MeSH terms

  • Acceleration
  • Analysis of Variance
  • Biomechanical Phenomena
  • Central Pattern Generators / physiology*
  • Female
  • Humans
  • Infant, Newborn
  • Infant, Premature / physiology*
  • Male
  • Respiratory Physiological Phenomena
  • Thoracic Wall / physiology*
  • Vestibule, Labyrinth / physiology*