Angioedema: patients experience and treatment relief

Abstract

Angioedema is defined as a swelling of the skin, mucosa and submucosa of the respiratory tract. It may also impair the intestinal epithelium and other mucous membranes. It can be potentially life-threatening if the upper respiratory tract is involved. In these cases emergency treatment is often required in particular if the pharynx and larynx are swollen. Beside the well-known etiologies of allergic angioedema, many forms of nonallergic angioedema are known and in the majority of these forms increased plasma and tissue concentrations of bradykinin play a critical role.