Rapid spectroscopic velocity quantification using periodically oscillating gradients

J Magn Reson. 2012 Jan;214(1):175-83. doi: 10.1016/j.jmr.2011.11.005. Epub 2011 Nov 17.

Abstract

In this work two spectroscopic methods are described which allow rapid flow velocity quantification in the presence of a parabolic velocity distribution. This method requires only a single excitation and is based on flow encoding by periodically oscillating gradients. In the shown spin echo variant additional refocusing pulses correct for field inhomogeneities. A theoretical model is introduced, which describes the course of the derived spectra even in high flow region, where a significant part of the encoded spins leaves the sensitive area of the coil during data acquisition (outflow-effect). It was demonstrated that both methods can quantify flow velocities within the velocity range of 1mm/s up to 36 cm/s in the presence of a parabolic flow velocity distribution. The maximum velocity of the parabolic distribution is indicated in this method by a peak in the acquired spectrum from which the velocity could be quantified. Flow velocity quantification by periodically oscillating gradients seems a reasonable and fast alternative to established imaging techniques.

Publication types

  • Comparative Study

MeSH terms

  • Algorithms*
  • Computer Simulation
  • Magnetic Resonance Spectroscopy / methods*
  • Models, Chemical*
  • Models, Molecular*
  • Oscillometry / methods*