Prevalence of persistent prehypertension in adolescents

J Pediatr. 2012 May;160(5):757-61. doi: 10.1016/j.jpeds.2011.10.033. Epub 2011 Dec 6.

Abstract

Objective: To measure the prevalence of persistent prehypertension in adolescents.

Study design: We collected demographic and anthropometric data and 4 oscillometric blood pressure (BP) measurements on 1020 students. The mean of the second, third, and fourth BP measurements determined each student's BP status per visit, with up to 3 total visits. Final BP status was classified as normal (BP <90th percentile and 120/80 mm Hg at the first visit), variable (BP ≥ 90th percentile or 120/80 mm Hg at the first visit and subsequently normal), abnormal (BP ≥ 90th percentile or 120/80 mm Hg at 3 visits but not hypertensive), or hypertensive (BP ≥ 95th percentile at 3 visits). The abnormal group included those with persistent prehypertension (BP ≥ 90th percentile or 120/80 mm Hg and <95th percentile on 3 visits). Statistical analysis allowed for comparison of groups and identification of characteristics associated with final BP classification.

Results: Of 1010 students analyzed, 71.1% were classified as normal, 15.0% as variable, 11.5% as abnormal, and 2.5% as hypertensive. The prevalence of persistent prehypertension was 4.0%. Obesity similarly affected the odds for variable BP (OR, 3.9; 95% CI, 2.5-6.0) and abnormal BP (OR, 3.4; 95% CI, 2.0-5.9), and dramatically increased the odds for hypertension (OR, 38.4; 95% CI, 9.4-156.6).

Conclusion: Almost 30% of the students had at least one elevated BP measurement significantly influenced by obesity. Treating obesity may be essential to preventing prehypertension and/or hypertension.

Publication types

  • Comparative Study
  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Adolescent
  • Analysis of Variance
  • Anthropometry
  • Blood Pressure Determination
  • Body Mass Index
  • Cohort Studies
  • Disease Progression
  • Female
  • Humans
  • Hypertension / diagnosis
  • Hypertension / epidemiology*
  • Logistic Models
  • Male
  • Mass Screening / methods*
  • Multivariate Analysis
  • Obesity / diagnosis
  • Obesity / epidemiology
  • Prehypertension / diagnosis*
  • Prehypertension / epidemiology*
  • Prognosis
  • Reference Values
  • Risk Assessment
  • School Health Services
  • Severity of Illness Index
  • Sex Distribution
  • Students / statistics & numerical data