Spectral domain optical coherence tomography findings in acute retinal pigment epitheliitis

Can J Ophthalmol. 2011 Dec;46(6):498-500. doi: 10.1016/j.jcjo.2011.09.012.

Abstract

Objective: To report spectral domain optical coherence tomography (SD-OCT) findings in 3 patients with acute retinal pigment epitheliitis (ARPE).

Design: Retrospective chart review.

Methods: Charts of three young patients with ARPE were reviewed.

Results: In acute stage, SD-OCT demonstrated abnormal hyperreflectivity involving the photoreceptor outer segment layer and hyporeflectivity involving the associated RPE layer in all cases. In chronic stage, SD-OCT showed decreased abnormal reflectivity. In one case with incomplete recovery of visual acuity, disruption of the photoreceptor inner and outer segment (IS/OS) junction was demonstrated in chronic phase.

Conclusions: SD-OCT confirmed that the outer segments of foveal photoreceptors and the associated RPE layer were the primary affected sites with ARPE. Detection of integrity of the foveal IS/OS line in resolved ARPE could be helpful in prediction of visual prognosis.

Publication types

  • Case Reports

MeSH terms

  • Acute Disease
  • Adult
  • Female
  • Fluorescein Angiography
  • Humans
  • Male
  • Prognosis
  • Retinal Photoreceptor Cell Outer Segment / pathology
  • Retinal Pigment Epithelium / pathology*
  • Retinitis / diagnosis*
  • Retinitis / physiopathology
  • Retrospective Studies
  • Scotoma / diagnosis
  • Tomography, Optical Coherence*
  • Visual Acuity / physiology