Disentangling crystallographic inequivalence and crystallographic forms of L-arginine by one- and two-dimensional solid-state NMR spectroscopy

Jose-Enrique Herbert-Pucheta; Henri Colaux; Geoffrey Bodenhausen; Piotr Tekely

doi:10.1021/jp209644k

Disentangling crystallographic inequivalence and crystallographic forms of L-arginine by one- and two-dimensional solid-state NMR spectroscopy

J Phys Chem B. 2011 Dec 29;115(51):15415-21. doi: 10.1021/jp209644k. Epub 2011 Dec 7.

Authors

Jose-Enrique Herbert-Pucheta¹, Henri Colaux, Geoffrey Bodenhausen, Piotr Tekely

Affiliation

¹ Ecole Normale Supérieure, Département de Chimie, 24 rue Lhomond, 75005 Paris, France.

PMID: 22148627
DOI: 10.1021/jp209644k

Abstract

Overlapping (13)C or (15)N solid-state NMR spectra from crystallographically different forms of L-arginine hydrochloride can be separated by exploiting differential proton T(1) relaxation in conjunction with cross-polarization. Dipolar (13)C-(13)C and (15)N-(15)N two-dimensional correlation experiments reveal resonances belonging to crystallographically and magnetically inequivalent molecules.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Arginine / chemistry*
Carbon Isotopes / chemistry
Magnetic Resonance Spectroscopy
Nitrogen Isotopes / chemistry
Protons

Substances

Carbon Isotopes
Nitrogen Isotopes
Protons
Arginine