This preliminary clinical study aimed to identify the impact of two border-molding techniques (dentist-manipulated and patient-manipulated) on patient satisfaction, the occlusal force at denture dislodgment, and number of pressure sores. Salivary flow rate and residual ridge resorption were analyzed as covariates. Thirty-six edentulous patients in need of a relining of their existing maxillary denture were included. After relining, no significant influence of the border-molding technique on any of the variables investigated could be identified. It can be concluded that the impact of the border-molding technique on patient satisfaction and denture function probably has been overestimated in the past.