CarGene: characterisation of sets of genes based on metabolic pathways analysis

Int J Data Min Bioinform. 2011;5(5):558-73. doi: 10.1504/ijdmb.2011.043033.

Abstract

The great amount of biological information provides scientists with an incomparable framework for testing the results of new algorithms. Several tools have been developed for analysing gene-enrichment and most of them are Gene Ontology-based tools. We developed a Kyoto Encyclopedia of Genes and Genomes (Kegg)-based tool that provides a friendly graphical environment for analysing gene-enrichment. The tool integrates two statistical corrections and simultaneously analysing the information about many groups of genes in both visual and textual manner. We tested the usefulness of our approach on a previous analysis (Huttenshower et al.). Furthermore, our tool is freely available (http://www.upo.es/eps/bigs/cargene.html).

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Databases, Factual
  • Gene Expression
  • Genes
  • Genome
  • Metabolic Networks and Pathways / genetics
  • Proteins / genetics*
  • Proteins / metabolism
  • Software*

Substances

  • Proteins