On the therapy effect for a stochastic growth Gompertz-type model

Math Biosci. 2012 Feb;235(2):148-60. doi: 10.1016/j.mbs.2011.11.007. Epub 2011 Nov 28.

Abstract

We consider a diffusion model based on a generalized Gompertz deterministic growth in which carrying capacity depends on the initial size of the population. The drift of the resulting process is then modified by introducing a time-dependent function, called "therapy", in order to model the effect of an exogenous factor. The transition probability density function and the related moments for the proposed process are obtained. A study of the influence of the therapy on several characteristics of the model is performed. The first-passage-time problem through time-dependent boundaries is also analyzed. Finally, an application to real data concerning a rabbit population subject to particular therapies is presented.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Models, Biological*
  • Population Dynamics
  • Rabbits / growth & development*
  • Stochastic Processes