Relationship between periodontal diseases and preterm birth: recent epidemiological and biological data

J Pregnancy. 2011:2011:164654. doi: 10.1155/2011/164654. Epub 2011 Oct 30.

Abstract

For ten years, the incidence of preterm birth does not decrease in developed countries despite the promotion of public health programs. Many risk factors have been identified including ethnicity, age, tobacco, and infection. However, almost 50% of preterm birth causes remain unknown. The periodontal diseases are highly prevalent inflammatory and infectious diseases of tooth supporting tissues leading to an oral disability. They influence negatively general health worsening cardiovascular diseases and diabetes. Periodontal diseases have been also suspected to increase the rate of preterm birth, but data remain contradictory. The objective of this review is to present the principal results of epidemiological, biological, and interventional studies on the link between periodontal diseases and preterm birth. The conclusions of this work underline the importance for the physician/obstetrician to identify women at risk for preterm birth and to address these patients to dentist for periodontal examination and treatment in order to limit adverse pregnancy outcomes.

Publication types

  • Review

MeSH terms

  • Bacterial Infections / complications
  • Cytokines / blood
  • Female
  • Humans
  • Maternal-Fetal Exchange / immunology
  • Periodontal Diseases / blood
  • Periodontal Diseases / complications*
  • Periodontal Diseases / epidemiology*
  • Periodontal Diseases / microbiology
  • Periodontal Diseases / therapy
  • Pregnancy
  • Pregnancy Complications, Infectious / blood
  • Pregnancy Complications, Infectious / epidemiology*
  • Pregnancy Complications, Infectious / microbiology
  • Premature Birth / epidemiology*
  • Premature Birth / etiology*
  • Prevalence

Substances

  • Cytokines