Histomorphometry in rodents

Methods Mol Biol. 2012:816:279-303. doi: 10.1007/978-1-61779-415-5_19.

Abstract

Bone histomorphometry remains an important tool to study the pathophysiology of bone disease and the cellular mechanism by which treatments work. Here, we review the methods for embedding, sectioning, staining, and analysis of bone sections in rodents.

Publication types

  • Review

MeSH terms

  • Animals
  • Bone Resorption
  • Bone and Bones / chemistry
  • Bone and Bones / cytology*
  • Bone and Bones / ultrastructure*
  • Calcification, Physiologic
  • Histological Techniques / methods*
  • Mice
  • Osteoclasts / cytology
  • Osteogenesis
  • Rats