Abstract
A new and general strategy for highly functional furo[3,4-c]coumarins and related furyl coumarin derivatives has been developed, which is based on an extraordinarily facile intramolecular Wittig reaction, starting from α,β-unsaturated ketones, tributylphosphine, and acyl chlorides. The phosphorus ylides were proposed to be the key intermediates for constructing the crucial furan ring, leading to a wide variety of substituted furyl coumarins in one step.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Chemistry Techniques, Synthetic / economics
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Chemistry Techniques, Synthetic / methods*
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Chlorides / chemistry
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Furans / chemical synthesis*
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Furans / chemistry
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Furocoumarins / chemical synthesis*
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Furocoumarins / chemistry
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Ketones / chemistry
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Phosphines / chemistry
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Photosensitizing Agents / chemical synthesis*
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Photosensitizing Agents / chemistry
Substances
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Chlorides
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Furans
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Furocoumarins
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Ketones
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Phosphines
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Photosensitizing Agents
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furan