[Is the traditional open donor nephrectomy in living donor renal transplantation still up to date?]

Wien Klin Wochenschr. 2012 Jan;124(1-2):39-44. doi: 10.1007/s00508-011-0094-9. Epub 2011 Nov 30.
[Article in German]

Abstract

Background: Living donor kidney transplantation is a well-established method to reduce time on the waiting list. Although the laparoscopic donor nephrectomy has already been established worldwide, more than 80% of the living donor nephrectomies are performed as a traditional open donor nephrectomy in Germany. The aim of our study was to analyze perioperative data and long-term outcome of donors and recipients following open donor nephrectomy.

Methods: From February 2004 to July 2008, a total of 51 open donor nephrectomies were performed in Tuebingen University Hospital. Forty-five data of corresponding transplant donors and recipients were analyzed. The Kocak classification which provides a format to compare postoperative complications after living donor nephrectomy was used.

Results: Five-year graft survival was 100%. No intraoperative complications occurred. Postoperatively Grad I complications were observed in 10 donors (22.2%). In the long term no major complications occurred. Two donors (4.4%) had newly diagnosed hypertension and required antihypertensive medication. None of the donors developed proteinuria. Right-sided transabdominal donor nephrectomy was associated with a shorter mean hospital stay compared to left-sided lumbar nephrectomy. (7.8 ± 2.4 vs. 9.2 ± 1.8 days, p < 0.05).

Conclusion: Open donor nephrectomy is a safe procedure with an excellent graft survival. Complication rates in our center are comparable to recent results in laparoscopic living donor nephrectomy. Therefore, the open donor nephrectomy remains important.

Publication types

  • Controlled Clinical Trial
  • English Abstract

MeSH terms

  • Disease-Free Survival
  • Female
  • Germany / epidemiology
  • Graft Survival*
  • Humans
  • Kidney Transplantation / mortality*
  • Living Donors / statistics & numerical data*
  • Male
  • Middle Aged
  • Nephrectomy / mortality*
  • Renal Insufficiency / mortality*
  • Renal Insufficiency / surgery*
  • Risk Assessment
  • Risk Factors
  • Survival Analysis
  • Survival Rate
  • Treatment Outcome