Composition and antioxidant activity of the polysaccharides from cultivated Saussurea involucrata

Int J Biol Macromol. 2012 Apr 1;50(3):849-53. doi: 10.1016/j.ijbiomac.2011.11.012. Epub 2011 Nov 22.

Abstract

Polysaccharides from cultivated Saussurea involucrata (CSIP) were purified, two major fractions (CSIP1-2 and CSIP2-3) were investigated for their molecular weights, monosaccharide compositions and in vitro antioxidant activities. The results suggested that the molecular weights of CSIP1-2 and CSIP2-3 were approximately 163.5 kDa and 88.6 kDa, respectively. CSIP1-2 was composed of glucose, galactose, xylose, rhamnose, arabinose and galacturonic acid with a molar ratio of 1.651:0.39:0.062:8.331:1.759:40.426. CSIP2-3 was composed of glucose, galactose, xylose, rhamnose, arabinose and galacturonic acid with a molar ratio of 0.762:0.657:0.112:5.587:0.318:44.655. Different scavenging activities on superoxide radical, DPPH radical and hydroxyl radical were observed in CSIP1-2 and CSIP2-3 at tested concentrations.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Free Radical Scavengers / chemistry*
  • Free Radical Scavengers / isolation & purification*
  • Free Radicals / chemistry
  • Molecular Weight
  • Polysaccharides / chemistry*
  • Polysaccharides / isolation & purification*
  • Saussurea / chemistry*
  • Saussurea / growth & development*

Substances

  • Free Radical Scavengers
  • Free Radicals
  • Polysaccharides