Abstract
We have functionalized the surface of gold nanocages with SV119, a synthetic small molecule specific to sigma-2 receptors, and then demonstrated the capability of this new class of conjugates for targeting cancer cells.
Publication types
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Research Support, N.I.H., Extramural
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Research Support, Non-U.S. Gov't
MeSH terms
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Cell Line, Tumor
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Gold / chemistry*
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Humans
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Materials Testing
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Nanocapsules / chemistry*
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Nanocapsules / ultrastructure
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Nanomedicine / methods*
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Nanostructures / chemistry*
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Nanostructures / ultrastructure
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Neoplasms, Experimental / chemistry*
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Neoplasms, Experimental / metabolism*
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Neoplasms, Experimental / pathology
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Particle Size
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Receptors, sigma / metabolism*
Substances
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Nanocapsules
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Receptors, sigma
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sigma-2 receptor
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Gold