Abstract
Poly(octanediol-co-citrate) elastomers containing high loading of lidocaine were synthesized at temperatures below 100 °C by means of using deep eutectic mixtures of 1,8-octanediol and lidocaine. The preservation of lidocaine integrity resulted in high-capacity drug-eluting elastomers.
This journal is © The Royal Society of Chemistry 2012
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Anesthetics, Local / administration & dosage*
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Chemistry Techniques, Synthetic
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Citrates / chemical synthesis
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Citrates / chemistry*
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Drug Carriers / chemical synthesis
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Drug Carriers / chemistry*
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Elastomers / chemical synthesis
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Elastomers / chemistry*
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Hot Temperature
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Lidocaine / administration & dosage*
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Polymers / chemical synthesis
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Polymers / chemistry*
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Solvents / chemistry
Substances
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Anesthetics, Local
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Citrates
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Drug Carriers
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Elastomers
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Polymers
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Solvents
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poly(1,8-octanediol citrate)
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Lidocaine