Association between seasonal influenza vaccination in 2008-2009 and pandemic influenza A (H1N1) 2009 infection among school students from Kobe, Japan, April-June 2009

Yuuki Tsuchihashi; Tomimasa Sunagawa; Yuichiro Yahata; Hideaki Takahashi; Takao Toyokawa; Fumito Odaira; Takaaki Ohyama; Kiyosu Taniguchi; Nobuhiko Okabe

doi:10.1093/cid/cir787

Association between seasonal influenza vaccination in 2008-2009 and pandemic influenza A (H1N1) 2009 infection among school students from Kobe, Japan, April-June 2009

Clin Infect Dis. 2012 Feb 1;54(3):381-3. doi: 10.1093/cid/cir787. Epub 2011 Nov 18.

Authors

Yuuki Tsuchihashi¹, Tomimasa Sunagawa, Yuichiro Yahata, Hideaki Takahashi, Takao Toyokawa, Fumito Odaira, Takaaki Ohyama, Kiyosu Taniguchi, Nobuhiko Okabe

Affiliation

¹ Field Epidemiology Training Program, National Institute of Infectious Diseases, Tokyo, Japan. yuuki.tsuchihashi@gmail.com

PMID: 22100572
DOI: 10.1093/cid/cir787

Abstract

We assessed the effect of seasonal trivalent inactivated influenza vaccination (TIV) on pandemic influenza 2009 (pH1N1)-related illness from April to June 2009 among 2849 students (aged 12-18 years). TIV was associated with an increase in the frequency of pH1N1-related illness among subjects (adjusted odds ratio, 1.47; 95% confidence interval, 1.14-1.89). TIV during the 2008-2009 season increased the risk of pH1N1-related illness from April to June 2009.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Adolescent
Child
Female
Humans
Influenza A Virus, H1N1 Subtype / immunology*
Influenza Vaccines / immunology*
Influenza, Human / epidemiology
Influenza, Human / prevention & control*
Influenza, Human / virology*
Japan / epidemiology
Male
Odds Ratio
Pandemics
Risk Factors
Seasons
Time Factors

Substances

Influenza Vaccines