Enhanced electrochemiluminescence of CdSe quantum dots composited with graphene oxide and chitosan for sensitive sensor

Biosens Bioelectron. 2012 Jan 15;31(1):369-75. doi: 10.1016/j.bios.2011.10.048. Epub 2011 Oct 31.

Abstract

A novel strategy for the enhancement of electrochemiluminescence (ECL) was developed by combining CdSe quantum dots (QDs) with graphene oxide-chitosan (GO-CHIT). The ECL sensor fabricated with CdSe QDs/GO-CHIT composite exhibited high ECL intensity, good biocompatibility and long-term stability, and was used to detect of cytochrome C (Cyt C). The results show that the ECL sensor has high sensitivity for Cyt C with the linear range from 4.0 to 324 μM and the detection limit of 1.5 μM. Furthermore, the ECL sensor can selectively sense Cyt C from glucose and bovine serum albumin (BSA).

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Biosensing Techniques / instrumentation*
  • Cadmium Compounds / chemistry*
  • Chitosan / chemistry*
  • Conductometry / instrumentation*
  • Cytochromes c / analysis*
  • Equipment Design
  • Equipment Failure Analysis
  • Graphite / chemistry*
  • Luminescent Measurements / instrumentation*
  • Oxides / chemistry
  • Reproducibility of Results
  • Selenium Compounds / chemistry*
  • Sensitivity and Specificity

Substances

  • Cadmium Compounds
  • Oxides
  • Selenium Compounds
  • Graphite
  • Cytochromes c
  • Chitosan
  • cadmium selenide