Dopaminergic polymorphisms and educational achievement: results from a longitudinal sample of Americans

Dev Psychol. 2012 Jul;48(4):932-8. doi: 10.1037/a0026313. Epub 2011 Nov 14.

Abstract

Although educational attainment has been found to be moderately heritable, research has yet to explore candidate genes for it. Drawing on data from the National Longitudinal Study of Adolescent Health, in the current study, we examined the association between polymorphisms in three dopaminergic genes (DAT1, DRD2, and DRD4), a dopamine index, and educational attainment. Statistically significant effects were found for DAT1, DRD2, DRD4, and the dopamine index for highest level of education. This study is the first to our knowledge that links measured genes to educational attainment.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Dopamine / metabolism*
  • Dopamine Plasma Membrane Transport Proteins / genetics*
  • Educational Status*
  • Female
  • Gene Frequency / genetics
  • Genotype
  • Humans
  • Longitudinal Studies
  • Male
  • Minisatellite Repeats / genetics
  • Models, Biological
  • Negotiating
  • Neuropsychological Tests
  • Polymorphism, Genetic / genetics*
  • Predictive Value of Tests
  • Receptors, Dopamine D3 / genetics*
  • Receptors, Dopamine D4 / genetics*
  • United States
  • Young Adult

Substances

  • DRD3 protein, human
  • DRD4 protein, human
  • Dopamine Plasma Membrane Transport Proteins
  • Receptors, Dopamine D3
  • SLC6A3 protein, human
  • Receptors, Dopamine D4
  • Dopamine