Fibrinogen unfolding mechanisms are not too much of a stretch

Martin Guthold; Samuel S Cho

doi:10.1016/j.str.2011.10.008

Fibrinogen unfolding mechanisms are not too much of a stretch

Structure. 2011 Nov 9;19(11):1536-8. doi: 10.1016/j.str.2011.10.008.

Authors

Martin Guthold¹, Samuel S Cho

Affiliation

¹ Department of Physics, Wake Forest University, Winston-Salem, NC 27109, USA. gutholdm@wfu.edu

PMID: 22078551
DOI: 10.1016/j.str.2011.10.008

Abstract

Molecular explanations for the extraordinary elasticity and extensibility of fibrin fibers are still lacking. Now, Zhmurov et al. (2011) use force spectroscopy experiments, and innovative simulations that match the time and force scales of these experiments, to study fibrinogen behavior under an applied force providing deeper insights into this process.

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