[The significance of the expression of Col IV and LN in nasal and paranasal sinus malignant tumor]

Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2011 Sep;25(17):771-4.
[Article in Chinese]

Abstract

Objective: To study the pathological relationship between the expression of Col IV and LN in nasal and paranasal sinus malignant tumor (NPMT).

Method: The immunohistochemical technique was used to detected the expression of Col IV and LN in NPMT, para-cancer tissues and non-cancer tissues.

Result: There was a significance on the expression of the Col IV and LN in NPMT, para-cancer tissues and non-cancer tissues (P<0.01), and no significance in endepidermis and soft connective tissue of the NPMT (P>0.05).

Conclusion: The Col IV and LN perhaps participate in tumorigenesis of NPMT, and may play the homoioplastic role in different pathological types of the NPMT.

Publication types

  • English Abstract
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Aged, 80 and over
  • Child
  • Collagen Type IV / metabolism*
  • Female
  • Humans
  • Laminin / metabolism*
  • Male
  • Middle Aged
  • Nasal Cavity / pathology
  • Nose Neoplasms / metabolism*
  • Nose Neoplasms / pathology
  • Paranasal Sinus Neoplasms / metabolism*
  • Paranasal Sinus Neoplasms / pathology
  • Young Adult

Substances

  • Collagen Type IV
  • Laminin