Erythrodermic psoriasis with regression after prophylaxis with isoniazid and antidepressant therapy: case report

An Bras Dermatol. 2011 Jul-Aug;86(4 Suppl 1):S141-3. doi: 10.1590/s0365-05962011000700037.
[Article in English, Portuguese]

Abstract

An 83 year old woman, exhibiting severe psoriasis, was treated conventionally (phototherapy, acitretin, and cyclosporine). After poor clinical results and significant changes in laboratory procedures, those treatments were suspended. She was then being prepared to be submitted to biological treatment, when preliminary results disclosed a 30 mm PPD. Complete improvement occurred [only] after introducing prophylactic therapy for tuberculosis and anti-depressive medication.

Publication types

  • Case Reports

MeSH terms

  • Aged, 80 and over
  • Antidepressive Agents / therapeutic use*
  • Antitubercular Agents / therapeutic use
  • Depressive Disorder / complications
  • Depressive Disorder / drug therapy*
  • Female
  • Humans
  • Induction Chemotherapy / methods
  • Isoniazid / therapeutic use
  • Male
  • Psoriasis / drug therapy*
  • Psoriasis / etiology
  • Sertraline / therapeutic use*
  • Tuberculosis, Cutaneous / drug therapy
  • Tuberculosis, Cutaneous / etiology

Substances

  • Antidepressive Agents
  • Antitubercular Agents
  • Sertraline
  • Isoniazid