Low prevalence of heterogeneous vancomycin-intermediate Staphylococcus aureus isolates among Connecticut veterans

Antimicrob Agents Chemother. 2012 Jan;56(1):582-3. doi: 10.1128/AAC.05024-11. Epub 2011 Nov 7.

Abstract

The Etest glycopeptide resistance detection identified two potential heterogeneous vancomycin-intermediate Staphylococcus aureus (hVISA) isolates from a screen of 288 methicillin-resistant Staphylococcus aureus (MRSA) isolates from patients at a Connecticut Veterans Hospital. However, the two isolates did not meet the criteria for hVISA by the population analysis profile-area under the curve analysis, arguing against routine screening for hVISA in this low prevalence population.

MeSH terms

  • Aged
  • Anti-Bacterial Agents / administration & dosage
  • Area Under Curve
  • Bacterial Typing Techniques
  • Connecticut / epidemiology
  • False Positive Reactions
  • Humans
  • Male
  • Methicillin-Resistant Staphylococcus aureus / drug effects
  • Methicillin-Resistant Staphylococcus aureus / genetics*
  • Methicillin-Resistant Staphylococcus aureus / isolation & purification
  • Microbial Sensitivity Tests
  • Prevalence
  • Staphylococcal Infections / drug therapy*
  • Staphylococcal Infections / epidemiology
  • Staphylococcal Infections / microbiology
  • Vancomycin / administration & dosage*
  • Vancomycin Resistance*
  • Veterans

Substances

  • Anti-Bacterial Agents
  • Vancomycin