Versatile trifunctional chemosensor of rhodamine derivative for Zn2+, Cu2+ and His/Cys in aqueous solution and living cells

Org Biomol Chem. 2011 Dec 21;9(24):8284-7. doi: 10.1039/c1ob06025b. Epub 2011 Nov 3.

Abstract

On the basis of rhodamine, a versatile trifunctional chemosensor RP has been synthesized. It can selectively and sensitively recognize Cu(2+) and Zn(2+) in different solutions. Based on the zinc-containing [RP@Zn(2+)] complex, it shows highly selective recognition for His/Cys. Fluorescent imaging of Zn(2+) in living cells was also obtained.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Coloring Agents / chemical synthesis
  • Coloring Agents / chemistry*
  • Copper / analysis*
  • Cysteine / chemistry*
  • HeLa Cells
  • Histidine / chemistry*
  • Humans
  • Molecular Structure
  • Rhodamines / chemical synthesis
  • Rhodamines / chemistry*
  • Solutions
  • Stereoisomerism
  • Water / chemistry
  • Zinc / analysis*

Substances

  • Coloring Agents
  • Rhodamines
  • Solutions
  • Water
  • Histidine
  • Copper
  • Zinc
  • Cysteine