[Occurrence of synthetic musks in human milk samples collected from Beijing]

Wei Sheng Yan Jiu. 2011 Sep;40(5):605-7.
[Article in Chinese]

Abstract

Objective: To investigate the occurrence of 13 kinds of synthetic musk and triclosan in breast milk samples collected from Beijing, and to estimate the exposure of breastfed infants.

Methods: Target compounds in 65 milk samples collected from 4 districts of Beijing in 2004 were analyzed by means of gas chromatography - tandem mass spectrometry (GC - MS/MS) and quantified by internal standards. The exposure of infants was analyzed statistically by SPSS software.

Results: HHCB, AHTN, OTNE, MT and Triclosan were detected in milk samples in the range of 0.6 - 174.1 ng/g lipid, with some difference in 4 districts. It is estimated that the intake of synthetic musks and triclosan for each infant from breast milk would be 13.5 - 3917 ng/d.

Conclusion: Commonly used synthetic musks and tricloson were generally detected in breast milk. Further study should be focused on monitoring and tracing the possible source of pollution.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Breast Feeding
  • Environmental Exposure / adverse effects*
  • Environmental Pollutants / analysis
  • Fatty Acids, Monounsaturated / analysis*
  • Female
  • Gas Chromatography-Mass Spectrometry / methods
  • Humans
  • Infant
  • Milk, Human / chemistry*
  • Perfume / analysis
  • Tandem Mass Spectrometry / methods
  • Triclosan / analysis*
  • Xylenes / analysis*

Substances

  • Environmental Pollutants
  • Fatty Acids, Monounsaturated
  • Perfume
  • Xylenes
  • musk
  • musk xylene
  • musk ketone
  • Triclosan