Manganese dioxide catalyzed N-alkylation of sulfonamides and amines with alcohols under air

Xiaochun Yu; Chuanzhi Liu; Lan Jiang; Qing Xu

doi:10.1021/ol202582c

Manganese dioxide catalyzed N-alkylation of sulfonamides and amines with alcohols under air

Org Lett. 2011 Dec 2;13(23):6184-7. doi: 10.1021/ol202582c. Epub 2011 Oct 31.

Authors

Xiaochun Yu¹, Chuanzhi Liu, Lan Jiang, Qing Xu

Affiliation

¹ College of Chemistry and Materials Engineering, Wenzhou University, Wenzhou 325035, China.

PMID: 22040008
DOI: 10.1021/ol202582c

Abstract

By simply running the reactions under air and solvent-free conditions using catalytic amounts of manganese dioxide, a practical and efficient N-alkylation method for a variety of sulfonamides and amines using alcohols as green alkylating reagents was developed.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Air
Alcohols / chemistry*
Alkylation
Amines / chemistry*
Catalysis
Manganese Compounds / chemistry*
Molecular Structure
Oxides / chemistry*
Sulfonamides / chemistry*

Substances

Alcohols
Amines
Manganese Compounds
Oxides
Sulfonamides
manganese dioxide