Development of an ICT-based ratiometric fluorescent hypochlorite probe suitable for living cell imaging

Lin Yuan; Weiying Lin; Jizeng Song; Yueting Yang

doi:10.1039/c1cc15762k

Development of an ICT-based ratiometric fluorescent hypochlorite probe suitable for living cell imaging

Chem Commun (Camb). 2011 Dec 21;47(47):12691-3. doi: 10.1039/c1cc15762k. Epub 2011 Oct 31.

Authors

Lin Yuan¹, Weiying Lin, Jizeng Song, Yueting Yang

Affiliation

¹ State Key Laboratory of Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering, Hunan University, Changsha, Hunan 410082, China.

PMID: 22037995
DOI: 10.1039/c1cc15762k

Abstract

We have judiciously constructed a novel ICT-based ratiometric OCl(-) probe capable of ratiometric imaging in the live cells based on the new OCl(-)-promoted de-diaminomaleonitrile reaction.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Cell Line, Tumor
Cell Survival
Drug Design
Electron Transport
Fluorescent Dyes / chemistry*
Humans
Hypochlorous Acid / chemistry*
Molecular Imaging / methods*
Spectrometry, Fluorescence

Substances

Fluorescent Dyes
Hypochlorous Acid