Gold and iron oxide hybrid nanocomposite materials

Chem Soc Rev. 2012 Mar 7;41(5):1911-28. doi: 10.1039/c1cs15213k. Epub 2011 Oct 28.

Abstract

This critical review provides an overview of current research activities that focused on the synthesis and application of multi-functional gold and iron oxide (Au-Fe(x)O(y)) hybrid nanoparticles and nanocomposites. An introduction of synthetic strategies that have been developed for generating Au-Fe(x)O(y) nanocomposites with different nanostructures is presented. Surface functionalisation and bioconjugation of these hybrid nanoparticles and nanocomposites are also reviewed. A variety of applications such as theranostics, gene delivery, biosensing, cell sorting, bio-separation, and catalysis is discussed and highlighted. Finally, future trends and perspectives of these sophisticated nanocomposites are outlined. Underpinning the fundamental requirements for effectively forming Au-Fe(x)O(y) hybrid nanocomposite materials would shed light on future development of nanotheranostics, nanomedicines, and chemical technologies. It would be interesting to investigate such multi-component composite nanomaterials with different novel morphologies in the near future to advance chemistry, biology, medicine, and engineering multi-disciplinary research (120 references).

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Biosensing Techniques
  • DNA / chemistry
  • DNA / metabolism
  • Drug Carriers / chemistry
  • Enzymes, Immobilized / chemistry
  • Enzymes, Immobilized / metabolism
  • Ferrosoferric Oxide / chemistry*
  • Gene Transfer Techniques
  • Gold / chemistry*
  • Humans
  • Immunoassay
  • Nanocomposites / chemistry

Substances

  • Drug Carriers
  • Enzymes, Immobilized
  • Gold
  • DNA
  • Ferrosoferric Oxide