This Statistical Brief presents data from the Healthcare Cost and Utilization Project (HCUP) on national estimates of hospitalizations for eating disorders over the decade from 1999–2000 to 2008–2009. First, eating disorder-related hospital stays are analyzed by payer, age, and sex, and hospital costs are provided. Second, the national estimates of eating disorder-related hospital stays are provided for each specific eating disorder category. Third, we examine the serious secondary diagnoses for hospital stays principally for eating disorder inpatients and principal diagnoses are examined when eating disorders are a secondary diagnosis. Although eating disorders may be under-reported in hospital discharge data, this information provides a baseline of information on these conditions. All tables include the years of our earlier Statistical Brief #70, 1999–2000 and 2005–2006, as well as the new estimates for 2007–2008 and 2008–2009. The statistical significance of all differences between estimates across years is indicated in all tables. To improve the accuracy, all annual estimates are two-year averages (e.g., the estimate for 1999–2000 is the average over 1999 and 2000).