One-pot and efficient synthesis of triazolo[1,2-a]indazole-triones via reaction of arylaldehydes with urazole and dimedone catalyzed by silica nanoparticles prepared from rice husk

Molecules. 2011 Oct 26;16(11):9041-8. doi: 10.3390/molecules16119041.

Abstract

A novel synthesis of triazolo[1,2-a]indazole-1,3,8-trione derivatives by reaction of urazole, dimedone and aromatic aldehydes under conventional heating and microwave irradiation and solvent-free conditions using silica nanoparticles prepared from rice husk ash as catalyst is described. The new method features high yields, multicomponent reactions and environmental friendliness.

MeSH terms

  • Aldehydes / chemistry*
  • Catalysis
  • Cyclohexanones / chemistry*
  • Indazoles / chemical synthesis*
  • Indazoles / chemistry
  • Microwaves
  • Molecular Structure
  • Nanoparticles / chemistry*
  • Oryza / anatomy & histology
  • Oryza / chemistry*
  • Silicon Dioxide / chemistry*
  • Triazoles / chemistry*

Substances

  • Aldehydes
  • Cyclohexanones
  • Indazoles
  • Triazoles
  • Silicon Dioxide
  • dimedone
  • urazole